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Plasma was assayed for active mouse GIP using an ELISA (27702

The takeaway is that individual response varies more than the averages suggest - some patients tolerate semaglutide better, others do better on tirzepatide, and the only way to know for certain is through guided clinical experience

For weight management, NICE recommends these medications as an adjunct to lifestyle modification in specialist weight management services, with specific BMI thresholds (typically 35 kg/m or 32.5 kg/m in certain ethnic groups) with comorbidities, and usually for time-limited periods (up to 2 years for semaglutide)