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These results suggest that the severe fluctuations in calcium signaling increase the susceptibility of substantia nigra neurons to damage and cell death

The multidistrict litigation has reached several procedural milestones: Over 1,300 active cases as of December 2024, with 79 new filings in November alone Monthly in-person status conferences with leadership counsel Rule 702 (Daubert) hearing scheduled for May 20, 2025, addressing expert testimony admissibility Science Day held in June 2024 for presentation of medical and scientific evidence Plaintiff leadership estimating 7,000 additional cases under active investigation The consolidation provides benefits for plaintiffs by streamlining discovery, coordinating expert testimony, and creating consistency in pretrial rulings

Position statement of the American Diabetes Association (ADA) and the European Association for the study of diabetes (EASD)

31 Beyond skin models, DHA has been shown to be cytotoxic to liver (HepG3), cardiac (Ac16), and bronchial epithelial (BEAS-2B) cells at concentrations as low as 1.5 mM to 7.5 mM