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, However, excessive TBMB usage may induce nonspecific modification of linear peptides

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Methods A three-step DSC method was used to measure the solubility of a small-molecule drug, voriconazole, in amorphous PLGA (Resomer RG 502H)

The paper provides other measurements like changes in drinking days and changes in heavy drinking days and changes in drinks per drinking day, but its the same story: Either no benefit or no difference