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Generally, introducing positively charged residues at the N- or C-terminus of peptides that do not affect the interactions is the commonly used method to enhance cell permeability

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Molecular Medicine Reports, 24(2), 605

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Cell Host Microbe 32, 276 (2024), Abstract Antioxidant, Anti-Apoptotic, and Anti-Inflammatory Effects of Farrerol in a Mouse Model of Obstructive Uropathy: J.Y

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The cardiovascular receptors may provide heart protection benefits observed in some clinical trials

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