Without offering a citation for a published paper or sharing any data, Sikirics 2025 review states that this clinical trial found that the drug was safe and well-tolerated in humans
In fact, they were originally thinking of adding more spots to further spread the Botox around to hit more nerve endings, but they settled on the current pattern to make it easier and less complex to do

Vitamin B12 Benefits Outside of its role in supporting weight loss, Vitamin B12 has a variety of health benefits: Brain Health Support: Vitamin B12 is essential for maintaining healthy nerve cells, which play a role in helping neurotransmitters produce and communicate Immune System Boost: Adequate levels of vitamin B12 help support a stronger, healthier immune system Promotes Heart Health: B12 helps regulate the bodys levels of homocysteine, amino acids that can increase your risk of heart disease Bone Health Support: Vitamin B12 also plays a role in maintaining your bone health, which can help prevent the onset of conditions like osteoporosis Vitamin B12 injections offer immediate improvements, helping increase your energy levels and improve your mood so that you can stay focused on and committed to your weight loss goals
Whats more likely happening: they were mildly deficient, the injection corrected that deficiency, and they feel well enough to move more and make better food choices