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Several pro-angiogenic factors were increased, including IL-6, IL-1, VEGF-D, VEGFR2, C-X-C motif chemokine ligand 11 (CXCL11), urokinase plasminogen activator surface receptor (uPAR), monocyte-chemotactic protein 3 (MCP-3), basic fibroblast growth factor (bFGF), tumor necrosis factor-alpha (TNF-) and MMP-9, and chemokine (C-C motif) ligand 5 (CCL5 or RANTES) (108)