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While the tissue and cellular localization of endogenous antioxidants, such SODs, catalase, GPx, and peroxiredoxins, is relatively well characterized, equivalent data for most exogenous (natural or synthetic) antioxidants are lacking

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Specifically, it has been found in "the cerebral cortex, cerebellum, hippocampus, thalamus, striatum, basal forebrain and the brainstem." These brain regions are linked to various cognitive processes from motivation and attention to memory and mood balance