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This intermediate is converted to fructose 6-phosphate (F6P) and subsequently to fructose 1,6-bisphosphate (FBP) by PFK1, a critical regulatory step in the glycolytic pathway

After a normalization procedure with ProgenesisQI, which we also previously described, we determined ions estimated to have derived from the eye drop-delivered drugs, as well as the metabolites of these drugs and their additives (Supplementary Table 1)

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