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However, it also stimulates cortisol and prolactin release at higher doses effects mediated through the same ghrelin receptor pathway but with less selectivity than ipamorelin, a key distinction in the sermorelin vs CJC-1295 vs ipamorelin comparison

Both require refrigeration because chemical stability depends on peptide bond strength and temperature, not pharmacokinetics

Some plaintiffs specifically claim they developed gastroparesis, a condition sometimes described as stomach paralysis, after taking the medication as prescribed

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