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However, certain populations are at higher risk of deficiency: Adults over 50 (reduced absorption capacity) Individuals following vegan or strict vegetarian diets Those with gastrointestinal conditions such as Crohns disease or celiac disease Individuals taking long-term acid-reducing medications (PPIs, H blockers) When oral supplementation is insufficient or absorption is compromised, vitamin B12 shots deliver the nutrient directly into the bloodstream, bypassing the digestive system entirely

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If the material dissolves and the solution returns to a clear (though possibly colored) state, it might have been minor crystallization

Pyridoxine is also considered safe during lactation in normal amounts, although exceedingly high doses might transiently suppress prolactin levels and were historically used (in much larger doses than nutritional needs) to suppress lactation