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NSAIDS (non-steroidal anti-inflammatory drugs) can trigger mast cells

No serious adverse effects have been consistently reported in clinical trials [1], [7]

This selectivity is crucial, as many other GH secretagogues also stimulate the release of ACTH and cortisol, which can lead to unwanted side effects

They downscale immune activation, kill effector T-cells, limit growth factor availability, and promote tissue repair returning the lung back to homeostasis ( Pulmonary Immune Dysregulation During HIV Infection Acute HIV and Lung Immunity Within a few hours of the transmission event, HIV begins to replicate in mucosal, submucosal, and draining lymphoid tissues