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Hsu SJ, Chung HC, Chang CH, Liao YC, Liu TW, Lin SM, et al

Thus, tau hyper-phosphorylation is another neuropathologic hallmark of AD and is linked to microglia activation and neuronal damage (Medeiros et al., 2010

The cumulative productivity impact over years of diagnostic delay exceeds $30,000 per patient in lost wages and employer costs (Nnoaham et al., 2011)

Study by Neuwirt et al [93] has shown an ability of proanthocyanidins extracted from grape seeds to suppress the growth of androgen-sensitive prostate cancer cell lines via a few mechanisms including regulating the expression of MAP kinase and activator protein 1