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While nausea, vomiting, and diarrhea commonly occur with tirzepatideparticularly during dose escalationsevere symptoms may require dose adjustment, temporary treatment interruption, or additional supportive care

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SLC6A14 is overexpressed in colorectal cancer (Lu et al., 2022), ER + breast cancer (Karunakaran et al., 2011), gastric cancer (Wang and Wang, 2022), pancreatic cancer (Schniers et al., 2022), and cervical cancer (Sikder et al., 2018), closely related to lower overall survival

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