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Specifically, null variants of the GSTM1 and GSTT1 alleles contain large deletions, and individuals who inherit two copies of the GSTM1 -null or GSTT1 -null alleles cannot produce the corresponding GST enzymes (14)

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Some users report continued improvement even after discontinuation, suggesting lasting tissue repair rather than just symptomatic suppression

The Radiation Therapy Oncology Group (RTOG) and the Common Terminology Criteria for Adverse Events (CTCAE) are two widely adopted grading systems utilized in clinical practice to assess radiation toxicity [11]