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When [Ca 2+ ] i changed within 5 min after addition of agents and their amplitudes were at least twice larger than the fluctuations of the baseline, they were considered responses

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In our study, NAC co-treatment not only ameliorated the impaired performance in NOR, Y maze, and MWM in chronic ethanol-exposed APP/PS1 mice, but also significantly alleviated the neuroinflammation, downregulated TNF- protein level and restored SYP, PSD95 and BDNF protein levels in the hippocampus of ethanol-exposed APP/PS1 mice, further suggesting the critical role of chronic ethanol exposure mediated oxidative stress and neuroinflammatory damage in AD pathology and the cognitive behavioral impairments

Its use is ideal for curbing cravings and adopting better meal management