There are several good options right now: semaglutide (Wegovy), a GLP-1 receptor agonist medication tirzepatide (Zepbound), a GLP-1/GIP medication liraglutide (Saxenda), a GLP-1 medication Several oral medications are also approved by the FDA for weight loss, including: semaglutide (oral Wegovy) orforglipron (Foundayo) phentermine (Suprenza) naltrexone-bupropion (Contrave) orlistat (Xenical/Alli) These are FDA-approved for adults who have a BMI of 30 or higher or a BMI of 27 along with a weight-related condition such as type 2 diabetes, hypertension, high cholesterol, obstructive sleep apnea, cardiovascular disease, or MASH (metabolic dysfunction-associated steatohepatitis, previously dubbed fatty liver)
Common ingredients in these injections include phosphatidylcholine (PPC) and sodium deoxycholate (DC)
Additionally, if prescribed, the plan includes compounded semaglutide, which contains the same active ingredient as Ozempic and Wegovy,* but can be an affordable alternative to brand-name weight loss injections
The sex-specific phenotype in Se metabolism is rather well-described the reader is referred to the review by Seale et al