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Some, such as atezolizumab (Tecentriq) and avelumab (Bavencio), target the protein PD-L1 present on cancer cells and prevent them from engaging the PD-1 protein on T cells, thereby disrupting the PD-1/PD-L1 axis and releasing the brakes on T cells

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PLoS ONE 17(3):e0266108 Umugire A, Nam YS, Nam YE, Choi YM, Choi SM, Lee S, Cho JH, Cho H-H (2023) Protective effect of avenanthramide-C on auditory hair cells against oxidative stress, inflammatory cytokines, and DNA damage in cisplatin-induced ototoxicity

Cardiovascular and Stroke Research Laboratory studies indicate that MT-1 may influence blood pressure regulation in hypertensive models without producing significant changes in normotensive controls