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In the open label adult clinical trials of patients with type 1 and type 2 diabetes, and in the open label pediatric clinical trial of patients with type 1 diabetes, percentages of adult and pediatric patients with type 1 diabetes randomized to TRESIBA who experienced at least one episode of hypoglycemia in clinical trials [see Clinical Studies ] and adults with type 2 diabetes are shown in Tables 3 and 4, respectively

Complementary, the high tumor accumulation was confirmed upon determination of the metal content in the respective organs by ICP-MS

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We learned from previous work conducted in our laboratory that the N-terminus of the molecule is critical for binding and activity [96-98]