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Patients who should not receive BPC-157 include: those with active or recent malignancies (due to angiogenic concerns), pregnant or breastfeeding women (no reproductive toxicology data in humans), patients on anticoagulation therapy (theoretical bleeding risk from angiogenesis at ulcer sites), and minors (no pediatric data of any kind)

Curr Obes Rep 14(1):48

While DPP-4 is expressed in mouse and pig pancreatic endocrine cells [26, 27] within the pancreatic duct, and in pancreatic alpha cells in humans [28, 29], glucagon is not one of its major substrates