There have been postmarketing reports of acute renal failure, sometimes requiring dialysis
10.1038/s41598-018-33385-z Summary Keywords nitazoxanide, methotrexate, hepatotoxicity, endoplasmic reticulum stress, rat Citation Mahmoud NM, Elshazly SM, El-shaarawy F, Zaitone SA, Aldahish AA, Ahmed GA, Fawzy MS, Aloyouni SY, Abed SY, Saeedi T and El-Sayed SS (2024) Nitazoxanide mitigates methotrexate hepatotoxicity in rats: role in inhibiting apoptosis and regulating endoplasmic reticulum stress
Thomas JD, Dattani A, Zemrak F, Burchell T, Akker SA, Gurnell M, et al
Z-Drugs (e.g., Zolpidem) Mechanism: Z-drugs are GABA-A receptor agonists that sedate and help with sleep initiation