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Many other research group leaders, including Pratt and Banerjee, studied in depth several aspects of the biochemical processes related to vitamin B12 cofactors [13,14,15,16,17,18,19]

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The symptoms of a vitamin B-12 deficiency may include: Fatigue, weakness Memory loss Depression Confusion Insomnia Shortness of breath Poor sense of balance Vision problems Diarrhoea or constipation Loss of appetite Cognitive functioning problems Beefy, red, smooth and sore tongue Sore mouth and/or bleeding gums Numbness and tingling of hands and feet Loss of hearing and tinnitus Pale, possibly yellowish pallor in light-skinned individuals