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NRF2 is a major regulator of redox homeostasis and response to oxidative stress

Oxygenated phosphatidylethanolamine navigates phagocytosis of ferroptotic cells by interacting with TLR2

Pro-inflammatory chemicals called cytokines (IL-6, TNF-) and prostaglandins contribute to fibroid growth and the heavy bleeding associated with them. Women with higher dietary inflammatory index scores show greater fibroid risk in observational data. Insulin and Insulin-Like Growth Factor Insulin resistance and hyperinsulinemia stimulate IGF-1, which acts on fibroid tissue growth receptors