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Combination L-NNA (20 mg/kg i.p.) with PTX (10 mg/kg i.p.) resulted in the significant increase in the number of gastric lesions and the fall in the GBF, as compared to those observed in PTX-treated rats without L-NNA administration

Though its not completely understood how immune tolerance to pregnancy is induced, there is convincing data that exposure to paternal antigens in semen prior to pregnancy allows the maternal immune system to develop tolerance by activation of maternal Treg cells

Those who are severely immunosuppressed can get PML, which can be fatal

Abstract Artesunate (ARS) induced significant reactive oxygen species (ROS) generation in HepG2, HeLa, and A549 lines