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These drugs work by slowing down how quickly the stomach empties and reducing hunger signals in the brain, particularly in the hypothalamus

Despite this, she joked that she immediately invested in the GLP-1 drug, knowing its popularity would skyrocket

In: Bhattacharya SK, editor

However, direct comparisons require caution because: Trial lengths differed Dosing protocols differed Patient populations differed Long-term orforglipron data is still developing A 5% to 10% reduction in body weight can still produce clinically meaningful improvements in blood pressure, insulin sensitivity, mobility, and metabolic health