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Derkach D, Kehtari T, Renaud M, Heidari M, Lakshman N, Morshead CM (2021) Metformin pretreatment rescues olfactory memory associated with subependymal zone neurogenesis in a juvenile model of cranial irradiation

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Effective transdermal drug delivery generally requires appropriate lipophilicity and molecular propertiesberberine's physicochemical characteristics are suboptimal for this route, primarily due to its ionic charge and poor lipid solubility

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