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In animal studies, free levels of T3 and T4 were reduced by approximately 30% (179), and a similar trend was observed in studies of human subjects

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In addition, JNKs (c-Jun N-terminal kinase) play an important role in insulin resistance, and p38 MAPK (p38 mitogen-activated protein kinase) has been shown to stimulate the uptake of glucose (Bennett and Lawan 2020)

Fluid overload is possible with rapid IV administration, especially for those with heart or kidney conditions