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Treatment focuses on addressing the underlying cause, controlling symptoms, and preventing complications particularly foot injuries in patients with diabetes who cannot feel pain normally

[DOI] [PubMed] [Google Scholar] 121.Hsieh CH, Hsieh HC, Shih FS, Wang PW, Yang LX, Shieh DB, et al

684 Mesenchymal stromal cell therapy alleviates persistent cognitive deficits caused by repetitive mild TBI by inhibiting ferroptosis, indicating it may be an effective TBI therapy strategy targeting ferroptosis

The idea of using a metric such as the clinically meaningful change can be applied to assess whether the outcome is not only statistically relevant, but would be meaningful to a person with a particular disease