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There are speculations that non-pathogenic commensal microorganisms, which co-evolved with humans, have been a source of immunomodulatory signals for the human body (the old friends hypothesis), and now prevent the development of immune-mediated chronic diseases (the hygiene hypothesis), with the proper composition of the microbiome promoting the maintenance of the bodys immune balance (the biodiversity hypothesis) [1, 39, 53, 54]

Simeons introduced the hCG diet in a 1954 medical journal article

NaBPC157 with its mucosal protective properties can be used for the treatment of conditions related to acute inflammation and chronic arthritis

Biochem Biophys Res Commun (2018) 503(3):168995