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Zepbound Kwikpen- tirzepatide injection, solution
The main symptom of keratosis pilaris is small, rough, dry bumps on the skin, which may give the skin a sandpaper-like texture and look like goosebumps or a rash
All patients experienced notable symptoms lasting multiple days
The primary molecular actions relevant to skin are: modulation of TGF- signaling (upregulating TGF-1 for collagen I/III synthesis while suppressing TGF-2 to prevent scarring), decorin upregulation for orderly collagen fibril assembly, MMP suppression paired with TIMP upregulation to preserve ECM integrity, and copper-dependent lysyl oxidase activation for collagen crosslinking
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