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The M1 phenotype, stimulated by lipopolysaccharide (LPS) and interferon- (IFN-), was used as a positive control, whereas the M2 phenotype, induced by interleukin-4 (IL-4), functioned as a negative control

In Europe, the lower end of range of B12 level is 400 and up

Schedule: Daily or every-other-day subcutaneous injections for 48 weeks

We focus on their molecular mechanisms, regulatory pathways, and cell-type-specific roles, and discuss emerging evidence linking the lactatelactylation axis to major neurological disorders, including ischemic stroke, neurodegenerative diseases, epilepsy, psychiatric disorders, and glioma