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Lovelace Jr, B

Pipeline implications If confirmed in humans, this could expand the use of these therapies far beyond obesity and diabetes

Crizotinib hydrochloride (PF-02341066 hydrochloride) inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with 50 IC s of 24 and 11 nM in cell-based assays, respectively