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Your current dose may be adjusted, or your doctor may make adjustments to your dosing schedule

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Of note, ATF6 cleavage and Xbp1 splicing were not altered upon G6PDH deficiency, indicating that ATF6-mediated or IRE1-mediated UPR were not activated (Extended Data Fig

They have been shown to redistribute heavy metals from other tissues to the brain, increasing brain neurotoxicity and leading to the loss of essential metals, such as zinc, or even hepatotoxicity due to serious side effects due to hepatotoxicity (134)