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Results showed that glutathione supplementation was again associated with suppression in lactate levels, while fatigue measures were also significantly decreased, compared to the placebo group

Under the joint regulation of existing mitochondrial nuclear DNA (nDNA) and mitochondrial DNA (mtDNA), new mitochondria are synthesized to replace damaged mitochondria, so as to repair mitochondrial structure, maintain mitochondrial function, increase antioxidant effect, reduce pathological oxidative stress and promote ATP production to meet the metabolic needs of eukaryotic cells under physiological and pathological conditions (Ferreira et al., 2019

In present work, we aimed to demonstrate the potential effect of GLP-1R on chondrocytes and elucidate its underlying mechanisms