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As a central kinase, GSK3 integrates multiple signaling pathways, thereby governing cellular processes ranging from glycogen synthesis and glucose metabolism to adipogenesis and inflammation [57,58,59], all of which contribute to the pathogenesis of obesity and its related metabolic complications

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Avi-Tag plasmid for improved biotinylation selectivity A common strategy to biotinylate proteins involves amine-reactive biotin derivatives that generate covalent bonds with positively-charged amino acids

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