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The dose escalation phase alone takes 16 to 20 weeks for most GLP-1 medications, and meaningful weight loss really begins at therapeutic doses
Range of Total Body Weight Loss, Fat Free Mass Loss and Skeletal Muscle Mass Loss by Weight Loss Method
Additionally, Wegovy's mechanism of slowing gastric emptying could theoretically affect the absorption rate of oral medications, though this is generally not clinically significant for alprazolam based on available data
While current research focuses predominantly on hepatocytes, potential Kupffer cell modulation in NASH-related inflammation and fibrosis warrants further investigation (78)
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