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Si bien los inhibidores de la colinesterasa han mostrado efectos positivos sobre las funciones cognitivas y las medidas del estado clnico global (82), una revisin sistemtica de ensayos aleatorios controlados no encontr que la lecitina sea ms beneficiosa que el placebo en el tratamiento de pacientes con deterioro cognitivo, demencia vascular, EA, o demencia mixta (83)