Metal chelation capacity is evaluated by assessing the ability of antioxidants to chelate metal ions, such as Fe 2 , which an elemental species, plays a role in promoting ROS generation within animal and human systems
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The key is consistency, the right dose, and pairing it with good habits like staying hydrated, eating a balanced diet, and using SPF daily
Importantly, high-dose regimensparticularly bolus or intermittent administrationhave not demonstrated clear clinical benefits in randomized controlled trials [271, 272].On the contrary, several studies have suggested that such strategies may increase the risk of adverse outcomes, including falls [273, 274]