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If youre taking a GLP-1 medication like Ozempic, Wegovy, or Saxenda, the best supplements to take are usually the ones that help protect muscle, fill nutrient gaps, support hydration, and reduce common side effects like fatigue or constipation

When appetite is low on a GLP-1 medication, focus on small meals with protein first, then add gentle carbohydrates, fruits, vegetables, and fluids

The findings may sound familiar to those who follow news about GLP-1s

severe or persistent upper abdominal pain should prompt urgent medical assessment [10] [11] Dehydration and acute kidney injury (AKI): gastrointestinal fluid losses can lead to dehydration, which may precipitate AKI, particularly in those with pre-existing renal impairment or those taking nephrotoxic medicines Delayed gastric emptying: this may affect the absorption of orally administered medicines, including contraceptive pills and thyroid replacement therapy [11] Injection site reactions: redness, bruising, or discomfort at the subcutaneous injection site Heart rate changes: increases in resting heart rate have been noted with GLP-1 class agents [14] [15] Hypoglycaemia: particularly if used alongside insulin or sulphonylureas Potential pancreatitis risk: a class concern with GLP-1 receptor agonists