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GLP-1 medications may not be suitable for individuals with: History of pancreatitis (not recommended per UK SmPCs) Severe gastrointestinal disease or gastroparesis (caution advised) Diabetic retinopathy, particularly for semaglutide (requires monitoring) Pregnancy, planning pregnancy, or breastfeeding (contraindicated

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Growth Hormone

GIP receptor antagonism reverses obesity, insulin re-sistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet