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Individuals with Vitamin B12 deficiency may notice improvement as deficiency is corrected

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Its substrate site-targeting mechanism inhibiting NNMT at the nicotinamide binding site provides selectivity over related methyltransferases and other enzymes in the NAD salvage pathway, making it a precise tool compound for studying NNMT-specific enzymatic activity in controlled laboratory systems

Even some meat eaters dont absorb it very well (4, Unlike other vitamins, the absorption of vitamin B12 depends on a protein produced in your stomach, called intrinsic factor