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According to the study of Shaaban et al., if ASD children aged 59 years are given a supplementation a 3 months supplementation with Lactobacillus acidophilus , Lactobacillus rhamnosus and Bifidobacterium longum, significant improvements emerge in ASD severity, gastrointestinal symptoms, and domains related to social interaction and communication

Several pathologies that affect the brain and kidneys have been associated with dysbiosis of the gut microbiota, and compared to the general population, individuals with CKD have a higher propensity for cognitive impairment (Drew et al., 2019)

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The standard schedule is a starting point, not a strict rule The 2024 NICE guideline NG239 on B12 deficiency in over 16s makes an important point: the optimal route, dose and frequency of B12 replacement have never been firmly established, and have often followed custom and historical practice