semaglutide didn't work for me reddit Is there one single person oral has worked for? : r/henrymeds A study in Nature Health

Total daily intake is what matters most

In addition, for subjects with a 2-h pre-dose fast, increasing the length of the post-dose fast did not seem to affect the absorption of oral semaglutide, with similar exposure levels observed between the 2 h30 min and 2 hnight treatment arms, indicating that the disruption of semaglutide absorption caused by food components in the stomach at dosing cannot be compensated by longer post-dose fasting

showed that 12-weeks of CLA supplementation (39.2% c9, t11 and 38.5% t10, c12) reduced body fat by 20% in healthy men and women [74], which could be due, in part, to the duration of the intervention, type of CLA composition, differences in the type and accuracy of the tools used for body composition assessment, and the inherent participant differences (i.e., genetic backgrounds)

Compounded versions of both are available through telehealth providers and compounding pharmacies with a prescription