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Measures that protect or restore the glycocalyx may reduce the vascular hyperpermeability, inflammation, and organ dysfunction associated with sepsis (131)
Nitrous oxide, a commonly used anesthetic, oxidizes and inactivates vitamin B 12 , thus inhibiting both of the vitamin B 12 -dependent enzymes, and can produce many of the clinical features of vitamin B 12 deficiency, such as megaloblastic anemia and neuropathy
Blood loss, especially from dialysis, infection, inflammation, and malnutrition, is another contributing factor
It stimulates the pituitary to release GH through the natural GHRH receptor, preserving the body's pulsatile GH rhythm rather than overriding it
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