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Future studies should involve larger-scale and more in-depth clinical and basic research to validate the efficacy of FMT and optimize treatment protocols, providing safer and more effective therapeutic options for SLE patients

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Moreover, another study demonstrates that iron imbalance in the proximal tubules enables to the promotion the accumulation of lipid hydroperoxides, and these iron-catalyzed oxidants can subsequently activate protein-and autoantibody-induced inflammatory transcription factors, ultimately leading to the production of stromal cells and cytokine/chemokine, and enhanced immune cell infiltration levels [14]