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Wegovy and Ozempic, side-by-side A few caveats about the drugs follow, but keep in mind with the marketplace driving much of the thinking, and clinical experience evolving, there may be changes in store: Wegovy is FDA-approved for chronic weight loss management in adults 18 years of age or older with a BMI of 30 or BMI 27 and at least one medical condition related to obesity (e.g., diabetes, hypertension, etc.)