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While agonism has a significant immunoregulatory and immunosuppressive function, the antagonism of [the] GLP-1 receptor is immunostimulatory, Paolo Fiorina, MD, PhD, research associate in the Department of Pediatrics Research in the Division of Nephrology Research at Boston Childrens Hospital and senior author of this study explained to Medical News Today

doi: 10.1007/s10787-020-00755-x

The authors identified only three published human pilot studies, all small and methodologically limited