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This condition affects 10% of all runners , making it the third most common running injury after shin splints and Achilles problems

Choline may increase cholinergic tone and could theoretically augment adverse reactions when combined with acetylcholinesterase inhibitors such as donepezil

Observational studies A large number of cross-sectional and prospective cohort studies have associated elevated blood homocysteine concentrations with measures of poor cognitive scores and increased risk of dementia, including Alzheimer's disease (reviewed in 67, 69)

More than half of both doctors and patients rated the B12 treatment as good or very good. It was also very well tolerated