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By leveraging patent thickets aimed at extending the market monopolies on their blockbuster drugs, these companies seek to maximize revenue streams while delaying the entry of low-cost generic alternatives

Biochim Biophys Acta 1830:31433153

Furthermore, liraglutide induces the activation of cleaved caspase-3 and downregulates Bcl-2 expression, implying that GLP-1RAs-mediated downregulation of BMP4 may promote apoptosis in CRC cells [71]

Gila monsters and starving rats: The drugmakers For the generation of biotech executives who presided over the burgeoning industrys first few decades, GLP-1 was the multibillion dollar idea that got away