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Its ability to penetrate the BBB, its metabolic stability, and its significant efficacy in restoring cognitive and motor functions in animal models of AD and PD, likely through modulating the HGF/c-Met system, position it as a highly promising therapeutic candidate for these debilitating neurodegenerative diseases [2]

An association of subacute BBB permeability with the migratory and angiogenic capacities of endothelial progenitor cells (EPCs) at day 7 after stroke has been shown in humans (68)

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