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Experimental evidence supports the importance of the MI/DCI ratio in ovarian physiology, as different formulations induce distinct changes in granulosa and theca cell architecture, with the physiological 40:1 ratio preserving follicular structure compared to DCI-enriched conditions ( Figure 3 )

Each TIMS cycle comprised 1 MS and 10 PASEF MS/MS scans across 64 DIA windows (25 isolations)

9 , F1000 Faculty Rev-239 (2020)

Notably, the tripartite inter-organ crosstalk between the gut, liver and skeletal muscle (i.e., the gut-liver-muscle axis) has recently been suggested to contribute to the development of sarcopenia in patients with cirrhosis (11)